Quandle Labs · Computational medicine

The moleculeand the ward.

Quandle Labs makes research software for protein science and operating software for hospitals. The same discipline runs through both: model the system properly, then show every step of the reasoning behind a result.

ChopprProtein analysis workflows
MDSim360Molecular dynamics in the cloud
MAENurse Command for units and wards
MelTheatres, workforce and market
DEWSEarly warning and remote monitoring

How we build

Every answer shows its working.

Reasoning

Steps, not verdicts

Each recommendation lists the records it read, the rules it applied and what argues against it. The person accountable can check it before they act.

One model

One picture of the hospital

Bookings, beds, rosters, theatre lists, supplies and outcomes data are joined into a single model. A change in one place reaches every view it affects.

Access

Nothing to install

Every product runs in the browser. No local software for researchers, no HPC queue, no scripting. Hospital products connect to the systems already in place.

Products

Two families, one standard.

Choppr stands on its own for protein research. MDSim360, MAE, Mel and DEWS form the Quandle Platform, built on a shared model of the patient and the hospital.

  • ChopprResearchReady-to-run protein workflows: structure prediction, design, docking and phylogenetics.
  • MDSim360Platform · ResearchProduction molecular dynamics from a PDB file, with analysis built in.
  • MAEPlatform · NursingNurse Command: patient flow, beds, staffing and departments on one screen.
  • MelPlatform · HospitalOT Management, Workforce and Mel Insight market analytics.
  • DEWSSolutionA predictive deterioration score with its own remote monitoring devices.

Research · Bioinformatics

Choppr

A new way to analyse proteins.

Choppr chains established tools into workflows and passes the output of one step straight into the next. Test an idea in minutes instead of weeks, without writing code, downloading databases or buying GPUs.

  • Homolog search and phylogenetic treeBLAST · Clustal Omega · RAxML
  • Design a thermostable proteinProteinMPNN · ThermoMPNN · FATCAT
  • Design a soluble proteinProteinMPNN · FATCAT
  • Alignment, trimming and treeClustal Omega · TrimAl · PhyML
  • Structure prediction and dockingESMFold · DiffDock

The Quandle Platform

Built on one model of the hospital.

Each product reads from the same model. Records, rosters, theatre lists, rooms and supplies are reconciled once, so MAE, Mel and DEWS work from the same facts and their recommendations never contradict each other.

SOURCES SHARED MODEL PRODUCTS Patient records Bookings & theatre lists Rosters & bank Beds & rooms Supplies & assets Published outcomes data Connected devices Patients, people,places, time MAENURSING Mel · OTTHEATRES Mel · WorkforceSTAFFING Mel InsightMARKET DEWSEARLY WARNING

Platform · Nursing operations

MAE

Nurse Command for day-case units and wards.

MAE holds the whole unit on one screen: every patient on the line from arrival to discharge, every bed at the hour you choose, every nurse's caseload and skills. When something will not fit, it says why and offers the moves that would.

Patient lineWhere every patient is, who is late and who is off the unit.
CapacityBeds at any hour today or next week, with the shortfall and the fixes.
Roster and bankGaps found against the plan; cover booked up to four weeks ahead.
DepartmentsImaging and tests tracked against each patient's theatre time.
Live reasoningEach check appears as it resolves, then the verdict and the options.
Patient lineEvery dot is a patient at their stage. Raised dots need attention.
ReasoningA late arrival, worked through step by step.
Move verdictDrag an arrival to a new time; MAE tests beds, rules and cover.
CapacityEvery bed at 13:00, the shortfall and three ways to close it.
DepartmentsImaging and tests, with timing verdicts against theatre.
Week aheadNext week's bookings by arrival time; the overbooked window shaded.
RosterCaseload, skills and fatigue for every nurse on shift.
Entity modelThe map of everything MAE reasons over, with live record counts.

Platform · Hospital operations

Mel

Theatres, workforce and market, in one system.

Mel runs the operating theatres of one hospital or a whole network, plans the people who staff them, and shows where the hospital stands in its market. Three modules, one model underneath.

Module · OT Management

Theatre lists that re-plan themselves

Mel watches every list against case pace and surgeon history, forecasts late starts and overruns, and proposes the move that costs least.

  • Day and week timelines across every theatre
  • Delay risk with the evidence and the options
  • Re-plan a day, or place an emergency with least disruption
  • Equipment, trays, implants and consumables tied to each case
TimelineFifteen theatres, 07:00 to 18:00. Late, at-risk and emergency cases marked.
BookingsProblems numbered on the list; Mel suggests where a case fits.
Delay riskCase pace, surgeon history and recovery, then the cheapest move.
Module · Workforce

Staffing set by the work ahead

Rosters for surgeons, anaesthetists and theatre nurses, planned against forecast case volume and matched to the skills each case needs.

  • Anaesthesia and theatre rostering
  • Leave checked against the volume forecast
  • Extra time detected, approved and passed to payroll
  • Sub-specialty matching for every list
Rostered load against forecast · illustrative
Anaesthesia82%
Scrub96%
Recovery71%
ODP108%
Surgeons88%
Module · Mel Insight

Where the hospital stands in its market

UK private hospital market analysis at procedure and hospital level. Built on PHIN-published data joined to clinical coding: volume, share, day-case rate, length of stay and fees.

  • Procedure board with trend and movers
  • Market share by provider and site
  • Your position against London or UK peers
  • Withheld and rounded cells treated as unknown, never as zero
Procedure boardVolume, change, sites and robotic share for each tracked code.
Trend and sitesTwelve-month trend, robotic share and every site's day-case mix.
ReasoningHow a ranking was reached, including what argues against it.
You vs peersRank, share and gap to the leader on every code.
Market shareProvider share for one procedure, London against the UK.

Platform · Molecular dynamics

MDSim360

Dependable MD simulation, online.

Upload a PDB file or CHARMM-GUI output and MDSim360 runs production-grade GROMACS: topology, solvation, ionisation, minimisation, equilibration and production MD. Most first runs start within ten minutes of upload. No installation, no HPC queue, no topology debugging.

RMSDRMSFSASARadius of gyrationValidated equilibration

Solution · Early warning and remote monitoring

DEWS sees it coming.

1050 ESCALATION THRESHOLD OBSERVED FORECAST +34 H −24 HNOW+24 H+48 H

Illustrative trajectory

A proprietary predictive score that forecasts deterioration two to 48 hours ahead.

Early warning scores read a snapshot and react once a threshold is crossed. DEWS reads the trajectory of a patient's vital signs, projects it forward with its uncertainty, and tells the team how long they have to act. The readings come from its own remote monitoring system, on the ward and at home.

01WearDEWS One on the patient, the cuff on schedule.
02StreamReadings arrive continuously and securely, ward or home.
03ForecastThe score updates with every reading and projects 48 hours ahead.
04AlertThe care team sees time to threshold and the signs driving it.
ECG ELECTRODE STATUS · LINK OPTICAL · SPO₂ · HR TEMP · MOTION
In development

DEWS One

Every vital sign. One sensor.

HRHeart rateSpO₂Oxygen saturation RRRespiratory rateT°Skin temperature ECGRhythmMOVMovement and posture

One wearable from pre-assessment to home. No leads, no bedside monitor, no manual rounds of observations.

Blood pressure

DEWS Cuff

Automatic readings on the schedule the care plan sets, sent straight into the score alongside DEWS One.

Early access

The first DEWS One units go to clinical partners.

  • Shape the device before it is final
  • Run DEWS on your own surgical pathway
  • First in line when units ship
Request early access →
Before surgery

Baseline

DEWS One is fitted at pre-assessment, so the score learns the patient's own baseline before the operation.

On the ward

Recovery

Continuous readings through the post-operative stay, the cuff on schedule, and alerts that carry the time to threshold.

After discharge

Home

Both devices go home with the patient. Same score, same care team, for as long as the pathway needs.

Company

Quandle Labs

We build computational tools for life sciences and healthcare: research software that removes the setup between a scientist and a result, and hospital software that turns a day's moving parts into decisions people can check.

EntityQuandle Labs Ltd
BasedUnited Kingdom
PortfolioPart of the Troika Labs portfolio
ProductsChoppr · MDSim360 · MAE · Mel · DEWS

Contact

See it running on your data.

hello@quandlelabs.com